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Selleck Chemicals compound wp1066 s2796
FCGBP promotes glioma growth by activating the JAK2/STAT3 signaling pathway. (A) WB analysis was performed to evaluate the expression levels of JAK2, p‐JAK2, STAT3, p‐STAT3, and c‐Myc in Vector, oeFCGBP, Vector + <t>WP1066,</t> and oeFCGBP + WP1066 groups. (B) Cell growth curves of different treatment groups were measured using the CCK‐8 assay. (C) EdU incorporation assay and corresponding histogram quantification were used to evaluate cell proliferation across different treatment conditions. Data were mean ± SD. Statistical significance was calculated by 2‐way ANOVA for A–C. ** p < 0.01, *** p < 0.001.
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FCGBP promotes glioma growth by activating the JAK2/STAT3 signaling pathway. (A) WB analysis was performed to evaluate the expression levels of JAK2, p‐JAK2, STAT3, p‐STAT3, and c‐Myc in Vector, oeFCGBP, Vector + WP1066, and oeFCGBP + WP1066 groups. (B) Cell growth curves of different treatment groups were measured using the CCK‐8 assay. (C) EdU incorporation assay and corresponding histogram quantification were used to evaluate cell proliferation across different treatment conditions. Data were mean ± SD. Statistical significance was calculated by 2‐way ANOVA for A–C. ** p < 0.01, *** p < 0.001.

Journal: Cancer Medicine

Article Title: FCGBP Promotes Glioma Growth by Regulating JAK2 / STAT3 /c‐Myc Pathway

doi: 10.1002/cam4.71617

Figure Lengend Snippet: FCGBP promotes glioma growth by activating the JAK2/STAT3 signaling pathway. (A) WB analysis was performed to evaluate the expression levels of JAK2, p‐JAK2, STAT3, p‐STAT3, and c‐Myc in Vector, oeFCGBP, Vector + WP1066, and oeFCGBP + WP1066 groups. (B) Cell growth curves of different treatment groups were measured using the CCK‐8 assay. (C) EdU incorporation assay and corresponding histogram quantification were used to evaluate cell proliferation across different treatment conditions. Data were mean ± SD. Statistical significance was calculated by 2‐way ANOVA for A–C. ** p < 0.01, *** p < 0.001.

Article Snippet: The compound WP1066 (S2796) was sourced from Selleck, China.

Techniques: Expressing, Plasmid Preparation, CCK-8 Assay